Powershell Active Directory modules loosing connectivity

When I first establish a Twingate connection i’m able to run AD PowerShell commands such as ‘Get-ADDomainController’. Somehow If I then try to run the ‘Active Directory Administrative Center’ it fails to connect after a long pause. There after i’m unable to then run the AD PowerShell commands. I do have a wildcard resource for DNS resolution such as ‘*.adomain.local’ which works well. I do notice that I do get the following error when this issue occurs:
user requested: wpad.adomain.local
DNS lookup failed
wpad.adomain.local could not be reached.

I would then have to logout/close the Twingate connection and re-connect to re-establish the ability to run AD PowerShell commands. Am I missing something?