Accessing a SMB2 connection over Twingate

We are trying to get a piece of software to connect to a Oracle database remotely over twingate. We have set up a AD connection outlined in this article How to Configure Active Directory with Twingate | Docs, which got us a step further but we are still getting SMB2 blocked error. The software give us the following error: ***********************************************************************
Fatal NI connect error 12537, connecting to:

TNS for 32-bit Windows: Version - Production
Windows NT TCP/IP NT Protocol Adapter for 32-bit Windows: Version - Production
Time: 19-FEB-2024 16:52:56
Tracing not turned on.
Tns error struct:
nr err code: 12206
TNS-12206: TNS:received a TNS error during navigation
ns main err code: 12537
TNS-12537: TNS:connection closed
ns secondary err code: 12560
nt main err code: 507
TNS-00507: Connection closed
nt secondary err code: 0
nt OS err code: 0

Any ideas how to stop the disconnect?